Medications


Nilotinib Oral Capsule

Brands: Tasigna

Uses

For treating cancer.

Instructions

Swallow the medicine without crushing or chewing it.

If unable to swallow the capsule, open the capsule and sprinkle onto applesauce. Eat the applesauce right away.

Take the medicine on an empty stomach.

Take on empty stomach - 1 hour before or 2 hours after eating.

It is very important that you take the medicine at about the same time every day. It will work best if you do this.

Store at room temperature away from heat, light, and moisture. Do not keep in the bathroom.

You may need to cycle between periods of taking the medicine and taking breaks from the medicine to allow your body to recover. Follow your instructions carefully.

Drink plenty of water while on this medicine.

Avoid grapefruit juice while on this medicine.

Do not take antacids 2 hours before or 2 hours after taking this medicine.

Medicines that lower stomach acid (used to treat indigestion, heartburn or ulcers) may prevent this medicine from working properly.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you forget to use a dose on time, just wait. Use the next dose at the usual time. Do not use 2 doses of this medicine at one time.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Do not suddenly stop taking this medicine. Check with your doctor before stopping.

Use effective birth control to avoid pregnancy.

Keep all appointments for medical exams and tests while on this medicine.

Do not take the medicine more than twice during 24 hours.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

This medicine is associated with a rare but very serious medical condition. Please speak with your doctor about symptoms you should look out for while on this medicine. Notify your doctor immediately if you develop those symptoms.

Some patients on this medicine have developed severe, life-threatening infections. Please speak with your doctor about the risks and benefits of using this medicine.

This medicine is associated with an increased risk of serious heart problems, heart attack, and stroke. Please speak with your doctor about the risks and benefits of using this medicine. Contact your doctor immediately if you experience chest pain or difficulty breathing.

This medicine may cause serious bleeding from the stomach or bowels. Stop this medicine and call your doctor immediately if you see any signs of bleeding. Bleeding can cause pain in the stomach, vomiting up liquid that looks like coffee grounds, and red or dark tarry stools.

Do not use the medication any more than instructed.

Contact your doctor if you notice a change in the amount or darkening of your urine.

This medicine may reduce your body's ability to fight infections. Avoid contact with people with colds, flu or other infections. Contact your doctor if you develop fever, cough, sore throat, or chills.

Speak with your health care provider before receiving any vaccinations.

Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.

Do not breastfeed while on this medicine.

Do not use this medicine if you are pregnant. If you become pregnant while on this medicine, contact your doctor immediately.

This medicine can cause birth defects. Speak with your doctor about birth control methods that should be used while on this medicine.

This medicine can hurt a new baby in the womb. If you become pregnant while on this medicine, tell your doctor immediately. Your doctor may switch you to a different medicine.

Do not take St. John's wort while on this medicine.

Call your doctor right away if you notice any unusual bleeding or bruising.

Do not share this medicine with anyone who has not been prescribed this medicine.

Some patients have serious side effects from this medicine. Ask your pharmacist to show you the information from the Food and Drug Administration (FDA) and discuss it with you.

Always refill this medicine before it runs out.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • constipation or diarrhea
  • lack of energy and tiredness
  • headaches
  • nausea and vomiting

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • severe or persistent abdominal pain
  • bleeding or bruising
  • chest pain
  • coughing up blood or vomit that looks like coffee grounds
  • dizziness
  • swelling of the legs, feet, and hands
  • fainting
  • fever or chills
  • severe or persistent headache
  • fast or irregular heart beats
  • kidney problems
  • signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
  • muscle cramps
  • muscle weakness
  • shortness of breath
  • bloody or dark, tarry stools
  • symptoms of stroke (such as one-sided weakness, slurred speech, confusion)
  • difficulty or discomfort urinating
  • blood in urine
  • blurring or changes of vision
  • sudden or unexplained weight gain

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Extra

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

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IMPORTANT NOTE: This document tells you briefly how to take your medicine, but it does not tell you all there is to know about it. Your doctor or pharmacist may give you other documents about your medicine. Please talk to them if you have any questions. Always follow their advice. There is a more complete description of this medicine available in English. Scan this code on your smartphone or tablet or use the web address below. You can also ask your pharmacist for a printout. If you have any questions, please ask your pharmacist. The display and use of this drug information is subject to Terms of Use. Copyright(c) 2022 First Databank, Inc.


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